Postoperative Pain Market Outlook, Trends And Future Opportunities (2024-2031)

Postoperative Pain Market is Forecasted to Hit US$ 32.3 Bn By 2031 | CAGR 7.2%

  • Date: 26 Mar, 2024
  • Author(s): Sagar Karlekar

Global Postoperative Pain Market is expected to reach US$ 32.3 Bn in 2031 with a growth rate of 7.2%. Postoperative pain management is a key component of surgical recovery. Increasing awareness regarding the negative impact of uncontrolled postoperative pain is driving growth.

The postoperative pain medications market comprises both prescription and OTC oral and parenteral formulations used to treat post-surgical pain. Key products include paracetamol, NSAIDs, opioids, local anesthetics, and adjuvants. The postoperative pain devices market consists of drug delivery systems like patient-controlled analgesia pumps, nerve stimulators, and cooling pain management devices.

Growth is driven by the rising volume of surgical procedures globally due to the aging population and increasing prevalence of chronic conditions. According to CDC, the number of surgeries performed in the US has risen by around 50% over the past decade. Advancements in minimally invasive techniques are also fueling market expansion.

The growing availability of abuse-deterrent opioids and emergence of newer NSAIDs provide significant opportunities for growth for drug manufacturers. Additionally, digitally integrated delivery systems allow personalized postoperative pain management. The market is expected to benefit from the robust product pipeline and innovation focused on multimodal approaches.

The postoperative pain market is poised for strong growth owing to the rising patient population, focus on enhancing recovery after surgery, product pipeline, and technology integration. Market dynamics are shifting toward patient-centric care and outcomes to minimize the burden of uncontrolled postoperative pain. Players are collaborating on integrated digital and drug therapies to enable personalized pain management. Minimally invasive approaches are helping reduce postoperative pain occurrence further boosting demand for newer therapeutic options.

Postoperative pain is pain that patients experience after a surgical procedure. It is a common medical condition that affects millions of patients worldwide each year.

Key Report Insights:

  • Major market driver: The rising number of surgeries globally is a major driver of the postoperative pain market. In 2023, around 200 million major surgeries were performed worldwide.
  • Companies are developing novel pain management drugs and devices like patient-controlled analgesia pumps to improve postoperative pain management. For example, Abbott recently launched a new smartphone-connected pain management system called PainNav.
  • Advances in minimally invasive surgical techniques like laparoscopy are helping reduce postoperative pain and driving demand for postoperative pain therapeutics.
  • The integration of digital technologies like wearables and apps to track and manage postoperative pain is an emerging trend in this market.


  • The global rise in the volume of surgical procedures, driven by the aging population and increasing prevalence of chronic diseases, is significantly driving the demand for postoperative pain management drugs and devices.
  • Technological advancements in drug delivery systems, nerve stimulators, cooling therapy, and patient engagement platforms is fueling market growth.


  • Growing adoption of minimally invasive surgeries like laparoscopy and robotic surgery that cause less post-surgical pain due to smaller incisions.
  • Increasing integration of digital technologies like smartphone apps and wearables for tracking and managing postoperative pain remotely.


Rising demand for abuse-deterrent formulations of opioid drugs to minimize risks of misuse presents lucrative opportunities.

Key Regional Insights:

  • North America accounted for over 40% market share in 2023 owing to high surgery volumes. Leading players like Pfizer, J&J, AbbVie have a strong presence in the region. Favorable reimbursement policies also contribute to growth.
  • Europe held the second largest share of over 25% in 2023 driven by established healthcare infrastructure and increase in same-day surgeries. Companies are also collaborating with hospitals to strengthen market access.
  • Major companies operating in the postoperative pain market globally are Pfizer, Johnson & Johnson, AbbVie, Novartis, Allergan, Eli Lilly, Endo International, GlaxoSmithKline among others. These players are focused on new product development, strategic collaborations, and geographic expansion.

Market Segmentation:

  • By Drug Class
    • Non-steroidal anti-inflammatory drugs (NSAIDs)
    • Opioids
    • Local anesthetics
    • Acetaminophen
    • Nerve blockers
    • By Route of Administration
    • Oral
    • Injection
    • Topical
    • Others (transdermal, inhaled, etc.)
  • By Distribution Channel
    • Hospital pharmacies
    • Retail pharmacies
    • Online pharmacies
    • Others (clinics, long-term care, etc.)
  • By Surgery Type
    • Orthopedic
    • Obstetric and gynecologic
    • General
    • Cardiac
    • Neurological
  • By End Use
    • Hospitals
    • Clinics
    • Homecare
    • Others (ambulatory surgical centers, long-term care centers, etc.)
    • Regions
  • By Region
    • North America
      • U.S.
      • Canada
    • Europe
      • Germany
      • U.K.
      • Spain
      • France
      • Italy
      • Russia
      • Rest of Europe
    • Asia Pacific
      • China
      • India
      • Japan
      • Australia
      • South Korea
      • ASEAN
      • Rest of Asia Pacific
    • Latin America
      • Brazil
      • Argentina
      • Mexico
      • Rest of Latin America
    • Middle East & Africa
      • GCC Countries
      • Israel
      • South Africa
      • North Africa
      • Central Africa
      • Rest of the Middle East


"The Postoperative Pain Market refers to the pharmaceuticals, biologics, and medical devices used for the treatment and management of acute pain after surgical procedures. It comprises drugs like opioids, NSAIDs, local anesthetics and devices such as nerve stimulation systems and patient-controlled analgesia pumps used to provide pain relief, reduce inflammation, and improve patient recovery after surgery. The market is driven by the rising number of surgeries worldwide and the need for effective postoperative pain control. Key players operating in this market include pharmaceutical companies like Pfizer, Novartis, J&J, and medical device makers such as Medtronic, Boston Scientific."

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