Chagas Disease Market Outlook, Trends And Future Opportunities (2024-2031)

Chagas Disease Market Expected to Reach US$ 496.5 Mn by 2031 | CAGR of 6.5%

  • Date: 28 Mar, 2024
  • Author(s): Sagar Karlekar

The Global Chagas Disease Market size is anticipated to reach USD 496.5 million by 2031, expanding at a CAGR of 6.5% over the forecast period. Chagas disease, also known as American trypanosomiasis, is a tropical parasitic infection that can lead to serious cardiac and digestive complications if left untreated. The disease is increasingly becoming a global public health concern.

The growth of the Chagas disease treatment market is majorly driven by the high prevalence of this disease in Latin American countries. Chagas disease causes significant morbidity and mortality in the 21 endemic countries of Latin America, with nearly 6 million people currently estimated to be infected worldwide. According to the Pan American Health Organization (PAHO), Chagas disease causes approximately 12,000 deaths per year in Latin America. The need for curative antiparasitic treatment and symptomatic care for the expanding patient pool is fueling the demand for pharmaceutical and diagnostic products.

Moreover, the lack of vaccines and preventive medications is further expected to drive research and development by biopharma companies and prompt investments towards new product launches. For instance, in April 2022, Entos Pharmaceuticals entered into a research collaboration agreement with the Drugs for Neglected Diseases Initiative (DNDi) to develop a new oral treatment for Chagas disease based on Entos' Fusogenix nucleic acid delivery platform. Such initiatives are creating a conducive environment for market growth by addressing the high unmet clinical needs.

Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by the protozoan Trypanosoma cruzi. It is spread mainly by insects known as Triatomine bugs. The disease is endemic to Central and South America, where it affects around 6-7 million people. If left untreated, it can be fatal.

Key Report Insights:

  • Major market driver: Increasing prevalence of Chagas disease in Latin American countries (around 6 million cases currently)
  • Companies are focused on developing new drugs, vaccines, and diagnostics tests. For example, Bayer is developing a new drug E1224, Chemo is testing a new vaccine, Abbott has developed a rapid diagnostic test.
  • Advances in diagnostics like PCR tests have improved early detection. New screening programs aid in prevention.
  • Growing awareness and control programs to tackle spread of the disease in endemic regions.

Key Growth Drivers:

  • The rising prevalence of Chagas infections in traditionally endemic regions like Mexico, Bolivia, Argentina due to factors like rural-urban migration is significantly contributing to market expansion. As per research published in PLOS Neglected Tropical Disease in August 2021, there are nearly 2.5 times more Chagas cases across the Americas than previously estimated by the WHO. This indicates a substantial disease burden.
  • Technological advancements in Chagas diagnostics such as PCR and rapid immunoassays are supporting the early detection of T.cruzi infections. The development and regulatory approval of point-of-care rapid tests that provide results within 20 minutes are improving access to screening in low-resource settings and aiding better patient management.
  • High unmet need for pediatric therapeutics also augurs well for market growth as pharmaceutical companies focus on expanding disease indications in children. For instance, in August 2021, Chemo Research received the FDA nod to include pediatric patients aged 2-12 years on the label of its Chagas disease treatment Benznidazole.

Key Trends:

  • Focus on developing vaccines and preventive medications for Chagas disease has increased significantly. Several candidates like Tc24, TSA-1 are currently under research.
  • Strategic partnerships between pharmaceutical players, academia, and Contract Research Organizations (CROs) are rising to accelerate Chagas drug development by utilizing synergistic capabilities.

Key Opportunities:

Development of novel therapeutics with higher efficacy and tolerability compared to the currently used benznidazole and nifurtimox presents an area of strong growth potential.

Key Regional Insights:

  • Latin America accounted for the largest share of over 70% of the global Chagas disease treatment market in 2024. High disease burden in countries like Brazil, Mexico, Argentina is fueling the demand. Leading companies like Bayer, Sanofi have a strong presence in the region.
  • North America accounted for around 15% revenue share in the Chagas disease market. The rising influx of migrant populations from Latin America is contributing to growth. Top companies operating in the region include Chemo Research, Merck, Abbott.
  • Prominent companies providing Chagas treatment and diagnostic products include Sanofi, Bayer, Eisai, Insud Pharma, Chemo Research, Abbott, Merck, Immune Therapeutics, Diaz de Santos, Exeltis, and Bio-Rad Laboratories among others. Strategic initiatives by these players continue to influence market dynamics.

Market Segmentation:

  • By Treatment Type 
    • Antiparasitic Medication
    • Symptomatic and Supportive Treatment
    • Vaccines
    • Others (stem cell therapy, gene therapy)
  • By Diagnostic Test
    • Microscopic Examination 
    • Molecular Tests (PCR)
    • Immunodiagnostics (ELISA)
    • Others (imaging, cultures)
  • By End-User
    • Hospitals 
    • Diagnostic Laboratories 
    • Academic and Research Institutes
    • Others (blood banks, NGOs)
  • By Regions
    • North America
    • Europe
    • Asia Pacific
    • Latin America
    • Middle East & Africa


"The Chagas disease market refers to the pharmaceutical, diagnostic, and other healthcare products used in the treatment, diagnosis, and prevention of Chagas disease or American trypanosomiasis. It includes drugs like benznidazole, nifurtimox, pipeline drug candidates, diagnostic tests like ELISA, molecular assays, rapid tests, medical devices, vaccines and other healthcare solutions targeting the Chagas disease patient population globally. The market is majorly centered around endemic regions like Latin America but is expanding as the patient pool rises in other regions as well. Key trends shaping the market include increasing research funding, growth of point-of-care diagnostics, demand for pediatrics therapeutics, and heightened disease control measures across both endemic and non-endemic countries. With better access and healthcare infrastructure, the market outlook remains positive."

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